Originally Posted by Golden Child
Is there a way to keep mame from exiting when you hit ESC when in Partial Keyboard Mode?

Yep, add this to your mame.ini:
confirm_quit              1

It'll be in the CORE MISC OPTIONS section.

BBC Model B, ATPL Sidewise, Acorn Speech, 2xWatford Floppy Drives, AMX Mouse, Viglen case, etc.