OPNA also has rhythm channels, not sure how MAME/MESS handle those, but Hoot and other japanese players need wave files sampled from the original chip (2608_bd.wav, 2608_hh.wav, 2608_rim.wav, 2608_sd.wav, 2608_tom.wav, 2608_top.wav).

Also, IIRC OPN is mono, while OPNA adds panning control.