I need to ask Mr. Do about how layouts take precedence over each other. Assuming they can, you could place an "INVERT" layout per LCD system in the layout folder, or a layout which makes the LCD per monochrome black-on-white. If they can't, then you remove the precompiled layout from the source and add one after the fact.
Still curious about whether all monochrome/greyscale LCD handheld systems have layouts that determine the coloring, or if some still need made.