Thexder's a good candidate for a MESS driver show-off, given the sheer number of ports. Game Arts & Square did Japanese versions on at least the PC-88, PC-98, X1, MSX, and NES, and then Sierra did versions on at least MS-DOS, Tandy 1000, Amiga, Apple II, Apple IIgs, and Macintosh, plus a Windows 95 version years later. We should be able to run all of those except the Win95 one, I think.